Ben Krantz

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Questions related from Ben Krantz

What is an appropriate statistical method to evaluate concordance in gene expression in paired specimens across a cohort?

I am looking to compare concordance in gene expression by whole transcriptome RNAseq in primary tumor specimens and patient tumor derived organoids. My plan is as follows: RNAseq counts will be...

11 November 2019 5,004 1 View

How can I calculate the power to determine a gene signature for sensitivity to a therapeutic in a screen of multiple samples?

I am looking to develop transcriptional signatures that are associated with sensitivity to therapeutics in a screen of patient tumor derived organoids. I am trying to figure out how to estimate...

11 November 2019 1,801 1 View