Contamination in LC-MS : m/Z 449.1 Th

We have a new contaminant in our LC-MS analysis of peptides eluted using 2D LC (high/lowPH RPLC) with an m/z value of 449.1, associated with a peak at 109.1, probably an in-source fragment. Anyone...

05 June 2013 9,062 2 View