Bala Subramaniyan

6 Questions 9 Answers 0 Followers

Questions related from Bala Subramaniyan

Which amine position will react with aldehyde to from schiff base?

In the below reaction the first starting material have two amine groups. In that which amine group will easily react with aldehyde to form schiff base? Reaction Concentration :- Eq.Mol Concentration

03 March 2018 1,226 16 View

How to reduce NO2 to NH2 without affect any other group in following reaction?

Hi, I have to reduce the NO2 group to NH2 group in the following reaction. Kindly suggest some good catalyst to reduce the NO2 to NH2 group without affecting any other position.

12 December 2017 1,477 42 View

Can i use AlCl3 a catalyst for cyclization reaction?

Aim of my work is to synthesis of Molecule 2 (Fluoroquinolone) using diphenyl ether as catalyst. Even after several attempts the molecule 2 fails to form due to deactivation of para position by...

12 December 2017 2,316 14 View

How to run molecular dynamics simulation for protein in discovery studio 3.5 software?

Hi, I have planned to study of molecular dynamics simulation for my homology modeled protein. Generally, most of Molecular dynamics (MD) simulations were carried out using GROMACS software. But i...

11 November 2017 4,964 4 View

Can i use diethyl ether instead of diphenyl ether? for cyclisation in Gould-Jacobs reaction?

Hi....i have synthesis of fluoroquinolones by Gould–Jacobs reaction method. In the first step for cyclisation reaction, generally Diphenyl ether was used in most of literature articles. Can i use...

11 November 2017 7,505 7 View

How to calculate the cavity volume or size in homology modeled protein?

I have developed a homology modeled protein and identified the cavity of the protein through bioinformatic software. unfortunately i couldn't calculate the cavity volume in my model protein. I...

07 July 2016 8,480 3 View