Ashraf Rangrez

7 Questions 27 Answers 0 Followers

Questions related from Ashraf Rangrez

Can Fibrinogen be polymerised without Thrombin?

Is/are there some other factors than Thrombin that can be used for the polymerization of Fibrinogen? I need to polymerize Fibrinogen but do not want to use Thrombin for this process but could not...

23 July 2020 4,530 1 View

Does anyone have experience with Co-IP using multiple antibodies at once?

I would like to know if anybody has ever tried performing co-immunoprecipitation using a mix of two or more antibodies against a partcular protein (I mean not separately, but together in one set...

01 July 2013 5,620 9 View

Is it possible that the transcriptional regulation of a given microRNA remains the same in different organs / tissues / cells?

I am wondering if every microRNA is regulated by the same transcription factors and regulatory mechanisms in all cell types it is expressed or every cell type has independent regulatory mechanism...

12 December 2012 9,150 28 View

Does pri-miRNA / pre-miRNA also come under the category of long non-coding RNAs (lncRNAs)?

Is there any relation between pri-miRNA and lncRNAs?

16 October 2012 4,997 16 View

Are pri-miRNA and pre-miRNA sequences coding for all validated mature microRNAs known?

There are almost 1000 or more microRNAs known for human / mouse / rat. I am wondering if the pri-miRNA and / or premiRNA sequences of all these microRNAs is also known? If yes, is there any...

16 October 2012 3,531 3 View

'Master' miRNA or 'super' miRNA?

miRNAs control various physiological and pathological processes, but what controls microRNAs? What controls their switch-on switch off? Is there any miRNA which can be termed as a "super" miRNA...

12 October 2012 3,864 12 View

Did anybody experience the problem of getting upregulation of Rcan1-4 expression but inhibition of calcineurin activity?

Or in other words, increased nuclear localization of NFAT in cardiomyocytes with no effect or rather inhibitory effect on NFAT-Calcineuring activity detected by luciferase assay? Is there any...

09 October 2012 8,648 1 View