Aruna Srinivasan

6 Questions 8 Answers 0 Followers

Questions related from Aruna Srinivasan

Uncompetitive and non-competitive inhibition of enzyme

If an inhibitor is uncompetitive, i.e inhibits by binding to ES complex, thus decreasing the Km and Vmax value and if another inhibitor is non- competitive, i.e it inhibits by decreasing the...

18 October 2013 8,616 1 View

What changes when activity is studies at a specific substrate concentration?

What does this statement mean - The uptake of substrate at a specific concentration may reflect both Km or Vmax or both. If Km of a transporter is independent of one of its regulator then the...

06 October 2013 8,666 7 View

Affinity and activity of enzyme substrate interaction?

When Km value for an enzyme is low, its affinity is considered to be high for its substrate. Considering this concept, does it mean that high affinity always leads to high product formation? Or is...

20 September 2013 7,587 7 View

Transport of glucose under high luminal concentration in the intestine?

Considering that the plasma glucose concentration is 5mM, under normal condition SGLT1 transports glucose uphill its concentration. However when luminal glucose concentration is high (above 5mM),...

20 July 2013 7,352 1 View

How can I know what are the possible post translational modification for a particular protein?

If affinity of a protein changes, it might alter the post translational modification or might add a modification to the protein. How do I find which are the possible changes that occur to affect...

28 December 2012 753 6 View

In regards to direct mechanism of regulation, how would you associate affinity with capacity of a transporter?

SGLT1 is a high affinity low capacity transporter whereas SGLT2 is a low affinity high capacity transporter, Is there a relation of affinity with capacity?

22 December 2012 6,702 3 View