Anuj Ranjan

5 Questions 35 Answers 0 Followers

Questions related from Anuj Ranjan

Crystals in plant extracts?

I have extracted certain plant material with methanol which has almost dried after evaporation of excess methanol. I have observed crystals in extract and when I try to dissolve same extract in...

12 December 2013 1,941 5 View

Importance of Pi interactions in Protein-Ligand interactions.

I have been working on certain protein-ligand interactions and have observed Tryptophan indole moiety is forming Pi-cation/Pi-Pi/Pi sigma with most of the ligands selected for studies. Is it...

04 April 2013 7,825 4 View

What is the best solvent system to run crude plant extract on TLC?

I am working with Verbenaceae family plants. What is the best solvent system to run crude extract on TLC?

01 January 2013 9,145 81 View

How to define the active site in AChE?

I am working with the Acetylcholinesterase enzyme, PDB ID 1B41. A few ligands are already bound in three different locations of the protein. Active sites according to UniProt are 234-Acyl-ester...

12 December 2012 5,744 12 View

Is energy minimization required if i use PDB models?

I am using a PDB model to screen some ligands. I have removed all the ligands attached previously in crystal structure. Is it necessary to run energy minimization to refine the models. If yes,...

12 December 2012 6,552 24 View