What is the best way to add TMSCl for the silylation protection of CARBOHYDRATES?

My issue is the following: I am trying to protect D-(+)-gluconic acid δ-lactone using TMCl, N-methylmorpholine (NMM) and THF as a solvent. However during the addition of TMSCl the lactone...

02 February 2019 1,988 2 View