Amala Kompella

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Questions related from Amala Kompella

Repeated T-cell stimulation/ T-cell Exhaustion model requirement for small molecules targeting check points?

Repeated T-cell stimulation/ T-cell Exhaustion is required for the in vitro T-cell functional assays development in case of the Immune check point inhibitors . Specifically for small molecules. If...

06 June 2024 8,394 0 View

Immune check points- in vitro assays - T-cells and stimulating agent optimization?

Pl. share insights into T-cell isolations optimizations/criteria and stimulation agent quantities required and incubation times optimization for check point inhibitors in vitro assays development....

30 May 2024 4,535 0 View

How to know type of the cancer cells for coculturing with PBMCs/T cells in IFNg restoration assay?

During development of small molecules for PD1/PDL1 axis disruption for in vitro coculturing assays is it random to take all PDL1 high expressing cancer cells to coculture with PBMCs/T cells ?

05 October 2023 1,879 0 View