3 Questions 4 Answers 0 Followers
Questions related from Alexander Howard
I am attempting to conjugate an antibody to a maleimide-drug conjugate. All the TCEP reduction protocols I find specify a protein concentration of 1-10 mg/ml in some sort of buffer (sodium borate,...
09 March 2018 5,014 1 View
I am looking to test various cdk inhibitors in cell lines and would like to be able to measure relative effects by following levels of phosphorylated target proteins. For example, the...
17 May 2017 6,550 3 View
The purpose is to conjugate a drug via its hydroxyl group to an antibody. Following linker cleavage, it is important for the linker to self-immolate in order to restore the drug to its original...
08 February 2017 2,116 4 View