Alex Boye

3 Questions 15 Answers 0 Followers

Questions related from Alex Boye

Which route of administration is suitable when using diethylnitrosamine (DEN) to induce hepatocellular carcinoma?

DEN shows liver-specific toxicity, as a result it is mostly used to induce various kinds of liver cancer. But there seem to be a lot of heterogeneity in the method of administration of DEN.

04 April 2014 8,737 12 View

Is there an inhibitor for precursors of TGF-beta 1 biosynthesis? If yes, what are these precursors and their respective inhibitors?

Transforming growth factor beta 1 has become a 'necessary evil' giving its role in normal homeostatic processes and pathophysiological states such as cancer. Many studies have focused on its...

04 April 2014 9,893 1 View

Which compensatory or otherwise quiescent signaling pathways may be stimulated upon complete inhibition of TGF-Beta/Smad signaling cascade?

The pleiotropic and ubiquitous TGF-Beta signaling has been associated with both normal body physiology and pathophysiology of a number of disease states including cancer. However what still...

03 March 2014 4,284 4 View