Are people with higher TMPRSS2 expression level, for example ones with Down syndrome suscepteble to COVID-19?

SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming. The site of the Transmembrane protease, serine 2 gene is on 21q22.3. People with down...

02 April 2020 492 11 View