Despite the high CO2 of the Paleozoic atmosphere, when CO2 levels were greater than 4000 ppmv (parts per million by volume), scientific evidence indicates a period of glaciation around 445 million years ago variously called the ''Early Palaeozoic Icehouse (EPI)'' and the ''Hirnantian Glaciation''.

1. Does this suggests that global climate may be independent of variations in atmospheric carbon dioxide concentration?

2. How may I explain this in view of the ''fact'' that concentration of atmospheric carbon dioxide remains one of the main factors in changes of the paleoclimate?

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