Hi Peter,

thank you for the answer. We work on cardiac cell-based therapy using AMI models in mice and swine. In this context, although sham-operated animals in which the surgical procedure is exactly reproduced as the experimental group without the treatment under study and reflect that observed effects are not merely a consequence of the surgery are informative, the inclusion of a sham-treated animal group is also valuable to obtain additional data, e.g. regarding possible therapeutic effects by implanted cells without the influence of myocardial damage...