I would like verify a data that was given to us by a genomic testing company regarding pharmacogenomics which states that "30% of adverse drug reactions have genomic associations".
Do we have a website or publication that contain this claim? I already googled it , but I can't find any leads.
Hello my research colleague this research, I hope you will benefit
Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges
Article Identifying genetic risk factors for serious adverse drug re...
Roneil, what company is involved? Do they reference their statements? You should be able to obtain a bibliography from them of anything that they cite, unless it’s a “data on file” reference.
That is a speculative figure most likely,
I am not aware of any studies reporting that figure.
Two reports that are likely of interest
"Approximately 50% of drug elimination from the body is due to the CYP450 system alone" Article Drug Metabolism and Variability among Patients in Drug Response
Speculation that reduction in ADRs by 10-15% may be possible by CYP450 genotyping alone Article Pharmacogenetics of cytochrome P450 and its applications in ...
Given that the CYP450 is one of many metabolic systems, and many other polymorphisms have been identified in other pharmacokinetics then the 30% figure is possible but would need widespread genotyping of most if not all currently known genes
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