2-aryl-2,3-dihydroquinolin-4(1H)-ones are Mannich bases (beta-aminocarbonyls) that can be synthesized via the L-proline-catalyzed one-pot reaction between o-aminoacetophenones and aryl aldehydes. This protocol provides an enantiomeric mixture (which can be separated to obtain the isomer of interest) with good reaction yields and tolerates both activating and deactivating substituents on aryl aldehydes.
Article L-Proline-Catalyzed One-Pot Synthesis of 2-Aryl-2,3-dihydroq...
You can find more methodologies to access 2,3-dihydroquinolin-4(1H)-ones in the following review.
Article ChemInform Abstract: Recent Syntheses of 1,2,3,4-Tetrahydroq...
If your question pertains to 4-quinolone, you will find a panel of synthetic approaches at
www.organic-chemistry.org > 4-quinolone
For the synthesis of quinolone ring containing Mannich bases heat 4-quinolone with formaldehyde with dimethyl amine for 3hrs., adding few drops of conc. HCl. The reaction is likely to occur at position -3 in 4-quinolone.
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