Are there any chemotherapeutic agents available for recurrent Fibromatosis in children ?

Fibromatosis is a benign but locally aggressive lesion. Several agents such as Tamoxifen, NSAID, Imatinib have been proposed in the management but none have a definitive role.

11 December 2016 5,855 1 View

Does anyone use neonatal pain assessment?

Neonatal pain is recognized to alter stress hormone levels and in turn influences neural development.

03 April 2014 8,260 1 View

Can an oral antibiotic be combined with an intravenous antibiotic?

Rational antibiotic usage...

02 March 2014 5,552 9 View

What is the policy for antibiotic usage in elective day care surgeries like herniotomy, patent processus ligation, circumcision, orchiopexy ?

Antibiotic Prophylaxis

02 March 2014 6,331 11 View

What are your opinions on the following drug combinations for anti-ulcer medication?

In the setting of prescribing anti-ulcer medication please comment on the following combinations : 1.Ranitidine with Omeprazole 2.Antacid with Ranitidine 3.Sucralfate with Omeprazole

02 March 2014 4,078 10 View

Can two EC50 values with different hill slopes be compared?

Hello, I fit a classical dose response curve Y=Bottom + (Top-Bottom)/(1+10^((LogEC-X)*HillSlope)) to my data (not related to inhibitors etc). The model I use is purely qualitative but it fits...

23 February 2021 8,155 5 View

Reaction condition to convert NH2 to COOH?

I need to couple Dopamine by NH2 end to silica nanoparticles coated by PEG-NH2, but first i need to convert the PEG-NH2 to COOH by using succinic anhydrous ... can you suggest a reaction condition ?

13 February 2021 2,768 4 View

Is this grounds for theophylline toxicity even though her plasma is within the therapeutic range? if it is, how is that possible?

A patient was given 300 mg Theophylline taken twice a day for the treatment of her bronchial asthma and has a positive clinical response. She has been compliant in taking her medication however,...

09 February 2021 3,489 3 View

How do i calculate the mean of patient age represented by year + months?

Dear all , I'm doing a pediatric study and the majority of sample's ages are repressented by year + months such as 6Y+4M. How can enter the data and calculate the mean in SPSS? Thank you for...

01 February 2021 570 10 View

Difference between assessing EC50 in presence of physiological levels of human serum albumin and alpha1 acid glycoprotein vs. % human serum?

01 February 2021 1,825 1 View

How can we increase awareness about Covid 19 prevention in our city among the local population?

The general public must be made aware of the mode of transmission, presenting symptoms and the measures that can be undertaken to prevent the spread of infection. Few options- Media, Webinars...

03 January 2021 3,538 13 View

What is the recommended age limit for primary posterior capsulotomy in pediatric cataract surgery?

In our centre, we are doing PPC even for older children upto 10-12 years of age and there seem to be no harm, rather beneficial and good outcomes. Please share your experiences.

27 December 2020 4,268 6 View

Are the receptor proteins on the surface of infected cells will increase or decrease the susceptibility of antivirals?

Are the receptor proteins on the surface of infected cells will increase or decrease the susceptibility of antivirals?

22 December 2020 3,242 4 View

How to convert Terapeutic Human Doses to Cell Experimentation Doses?

"Toxicological evaluations revealed that Cur is found to be pharmacologically safe, even up to 12 g per day, as reported by several animal studies and in phase-I clinical trials Similarly,...

07 December 2020 3,012 1 View

Which neuronal cell line contain D1R?

I'm formulating a drug delivery system that could stimulate Dopamine receptor, For that i need to choose cell line that contain D1R and could be simulated using my delivery system... I have read...

20 November 2020 9,104 2 View