Hi Fakhr,

Natalia has already mentioned some good ones! There is a software called KNIME (http://www.knime.org/). This platform is free to download and provides a workflow for the entire data process (from curating your data to modelling it). Its a good software and has a friendly user interface, additionally there are user guides on the website.

Hope that helps!

Danielle

We can generate the descriptors at www.vcclab.org/ . These descriptors can be treated even in excel or xlstat to generate the QSAR model !!!‎

We can generate thousands the descriptors at www.chemosophia.com now for free

There are in fact several free software for calculating descriptors such as

1. PaDEL

http://padel.nus.edu.sg/software/padeldescriptor/

2. Jcompoundmapper

http://jcompoundmapper.sourceforge.net/

Or if you use scripting language like Python, then I highly recommend

1. CDK and Rdkit from within Cinfony package

https://code.google.com/p/cinfony/ 

2. PyDPI

http://sourceforge.net/projects/pydpicao/

way2drug

Hello

Check in these links. It might help you.

https://www.click2drug.org/

Good Luck.

Hi. You can used DRAGON 7 from kode bioinformatics for your QSAR applications. They share the license version with you for 1 year.

You can have a look at Alvascience solutions (https://www.alvascience.com/), a free version of alvaDesc for the calculation of molecular descriptors is available on OCHEM - Online Chemical Modeling Envinronment (https://ochem.eu/home/show.do).

Try the freely available sotware LQTAgrid (4D-QSAR)(http://lqta.iqm.unicamp.br/portugues/siteLQTA/LQTAgrid.html).