Hi, the 2 most popular symptom questionnaires in MS are the EDSS and the MSFC. Both have advantages and limitations and the selection will depend on your specific question or trial. Both of the mentioned assays can be applied longitudinally without excessive training effect. The cognitive component of MS may be underestimated in both tests, which are somewhat focussed on the neuromotor dysfunction. For an overview I can recommend the recent review series in Lancet Neurology.

That's great, thank you both. I'll check them out.

Hi Joshua,

I guess it depends if you want to go for rater-based outcome parameters or patient-based outcome parameters for moitoring. Ideally it is suggested to use both.

While EDSS and MSFC are still the established rater-based outcome parameters that are accepted and often mandatory in the field, they really have theirs problems. I actually prefer the SCRIPPS to the EDSS.

In regard to patient-based outcome parameters maybe you can use this overview on patient-related outcome parameters http://www.ncbi.nlm.nih.gov/pubmed/23398571.  Here MSIS-29 and HAQUAMS are recommended, for the HAQUAMS also a German version exists in case you are looking at a German cohort. 

Best, 

Klarissa

Hi Joshua,

I know that in Switzerland a group of therpists developped a patient self-reported questionnaire about ADL for treatment follow up.

The MSQPT (Multiple Sclerosis Questionnaire for Physiotherapists) should be available in GErman and French, but I don't know how the questionnaire is validated for research.

May be this is a "track you can follow" and I hope this helps ;-)!

Kind regrads

Thomas

Thanks Klarissa,

That was super helpful. We're setting up a little online research study with MS and would like participants to complete a preliminary survey prior to the actual studies to assess their symptoms. So it sounds like perhaps the MSIS or HAQUAMS would be best. I haven't had time to check into any of the options yet.

Thanks again,

Joshua

Hi Joshua, I think the most comprehensive collection of tools to use for assessment of MS people are in this website:

http://www.nationalmssociety.org/For-Professionals/Researchers/Resources-for-Researchers/Clinical-Study-Measures

For repeatedly (after each weekly treatment) usage with MS patients I have found also useful the MYMOPS

http://www.bris.ac.uk/primaryhealthcare/resources/mymop/

Multiple Sclerosis Quality of Life Inventory (MSQLI)

https://www.nationalmssociety.org/For-Professionals/Researchers/Resources-for-Researchers/Clinical-Study-Measures/Multiple-Sclerosis-Quality-of-Life-Inventory-(MSQL

Hi,

I suggest EDSS and the MSFC. Moreover, BICAMS and FSS are suitable.

Cheers,