Wistar rat, diabetes
You can use Streptozotocin (Streptozocin, STZ) an anti cancer drug to induce type 1 diabetes with a high dose as well as type 2 diabetes with multiple low doses. It is enough to have a simple search in scholar Google.
You may look at a related topic here:
https://www.researchgate.net/post/How_to_Induce_permanent_diabetes_by_streptozotocin_in_wistar_rats2
And at this paper, which uses a different method (10% fructose instead of streptozotocin): http://www.jdmdonline.com/content/12/1/9
Hope it helps!
Yes, by Streptozotocin(STZ) (20 mg/kg-70 mg/kg)intraperitoneally
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