You can either use the MATLAB toolbox (http://www.mathworks.de/products/bioinfo/description4.html and http://www.mathworks.de/products/bioinfo/demos.html?file=/products/demos/shipping/bioinfo/cancerdetectdemo.html) or you can also write your own codes in matlab which is very easy not so much complicated.
Well, your questions are really difficult to answer, I guess, since you don't report the kind of files you have to work with. It would be very helpful fo me (us) that you report exactly how your data look like, and what is the file extension of your raw data.
import RAW files to MATLAB: you have load command for example if you have a data file called data.txt
you can write, 'load data.txt' then you create a variable named data. Matlab is performed for excel files, binaries file. If you want more information about 'load' command write 'doc load' or 'help load'
We have importers for .RAW and analyze this kind of data quite often using chemometrics techniques (e.g., via PLS_Toolbox). But your question is difficult because the correct approach is often data/application specific. For example, if you have correlated peaks then you might be able to use multivariate techniques to increase the S/N and do some noise filtering. You might also be interested in Poisson scaling. - good luck!