Dear colleagues, we (with my collaborators) develop an interesting multi-wallet carbon based nanosensors for for amplification-free DNA detection. According to literature this kind of sensors is non very popular but there are enought evidence of their potential in molecular diagnostics. May be anybody use (used) nanosensor in their work? Could you give me feedback? We would like to improve and adopt our sensors for clinical diagnostics.
Now we able to recognize SNP's and specific viral/bactrerial NA in samples after routine column-based NA purification. We do not use any amplification. The detection is non-fluorescent.