I'm interested to do one pot reaction with 2 steps, the starting material for second step is epoxide and the system is very sensitive to proton source like acids and water and I looking for proper reagent.
Dimethyl dioxirane (DMDO) or if it is an electron-poor olefin then nucleophilic epoxidation (TBHP + BuLi). I hope I helped.
M(acac)2 + O2 moléculaire = systhème de Mukayama pour époxydation
M = Ni, Co, Fe, ....
I can confirm the methods that are suggested by Florenci González and El Farrouji Amine.
If I understood you right, you want to perform olefin epoxidation in an aprotic medium. In this case, it is a question whether water-free DMDO can be prepared in a safe way, because this stuff was once considered a fool's home-made explosive. I did my master thesis in aerobic epoxidation (with O2 as the oxidant). It worked with styrene at 60-120°C and 1bar pO2, even without addition of transition metal catalysts. However, 1) yield and selectivity both are poor, 2) a co-reductant, e.g. DMF, is a mandatory ingredient in the reaction medium, and 3) the work-up is a mess since by-products range from carbonyl compounds to polymers.
Maybe the Katsuki-Jacosen-epoxidation could work for you: with NaOCl as oxidant (here comes the water-free-problem again...), Mn-salen catalyst and CH2Cl2 as solvent.
If your synthesis strategy is flexible, you may replace the epoxidation with
a) the formation of the epoxide from the respective vicinal diol, or
b) the addition of an ylide to a carbonyl compound.
Good luck and good patience.
H2O2 is a good reagent to produce epoxide with different catalyst ( Mo,W, Se, TS1...
to resolve the problem of water a azeotropic distillation during the reaction is a good option
to decrease the effect of acid,addition of small quantity ofaromatic amine ( pyridine, lutidine ....)
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